Search results for "Cell entrapment"
showing 2 items of 2 documents
Dipolar Rings of Microscopic Ellipsoids: Magnetic Manipulation and Cell Entrapment
2016
We study the formation and dynamics of dipolar rings composed by microscopic ferromagnetic ellipsoids, which self-assemble in water by switching the direction of the applied field. We show how to manipulate these fragile structures and control their shape via application of external static and oscillating magnetic fields. We introduce a theoretical framework which describes the ring deformation under an applied field, allowing to understand the underlying physical mechanism. Our microscopic rings are finally used to capture, entrap and later release a biological cell via magnetic command, i.e. performing a simple operation which can be implemented in other microfluidic devices which make us…
Self-assembling and auto-crosslinkable hyaluronic acid hydrogels with a fibrillar structure
2008
Abstract A hyaluronic acid derivative bearing pendant l -benzoyl-cysteine portions (with a derivatization degree equal to 10 mol.%) was synthesized by linking N,N′-dibenzoyl- l -cystine to the polysaccharide and then reducing its disulfide bridge to thiol groups. The formation of π–π stacking interactions between the benzoyl moieties was studied by fluorescence spectroscopy as a function of polymer concentration and oxidation time. The efficiency of oxidation of thiol groups to disulfide bridges occurring in phosphate buffer pH 7.4, was determined by colorimetric assays. The hydrogel formed by means of oxidative crosslinking has shown the presence of fibrillar aggregates as detected by ligh…